Hosted by the Oxford–Cambridge Supercluster, the conference brings together senior figures from government, industry, academia and investment to explore how the UK can maximise its potential as a globally competitive scientific powerhouse. Eighteen months into Government’s Oxford–Cambridge Growth Corridor programme, this year’s conference marks a transition, from commitment and ambition to delivery and momentum. What was once a bold vision for transforming the region into a global innovation powerhouse is now moving firmly into implementation.